Fri May 16 2025

18 articles - From Friday May 09 2025 to Friday May 16 2025

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Inflamm Bowel Dis

Risk Factors for Venous Thromboembolism in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis by Phase of Care.

We identified multiple risk factors associated with VTE across different phases of care. This work will help in the development of future predictive models to guide thromboprophylaxis in IBD.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Adherence to EAT-Lancet diet, biological aging and life expectancy in the UK Biobank: a cohort study.

Adherence to EAT-lancet diet is linked to delayed biological aging and increased life expectancy, regardless of genetic predisposition. This suggests that promoting this sustainable dietary pattern could serve as a practical nutritional strategy for enhancing healthy longevity.

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Assessing the adherence and acceptability to iron and folic acid versus multiple micronutrient supplements during pregnancy: A cluster-randomized non-inferiority trial in Cambodia.

Both IFA and MMS were highly acceptable, yet adherence to MMS was superior to IFA. These findings support the transition from IFA to MMS in Cambodia.

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Impact of Dietary Cholesterol from Eggs and Saturated Fat on LDL Cholesterol Levels: A Randomized Cross-Over Study.

Saturated fat, not dietary cholesterol, elevates LDL cholesterol. Compared with consuming a high-saturated fat diet with only one egg per week, consuming two eggs daily as part of a low-saturated fat diet lowers LDL concentrations, which may reduce CVD risk. However, this effect on CVD risk may be mitigated, at least in part, by a reduction in less-atherogenic large LDL-particles and an increase in more atherogenic small LDL-particles. Clinical trial registration

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Maternal prenatal nut and seafood consumption and child neuropsychological function from 4 to 15 years of age: a population-based cohort study.

Maternal diet at pregnancy and omega-3 intake may support long-term cognitive development in children and adolescents.

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One-carbon metabolism, insulin resistance, and fecundability in a Singapore prospective preconception cohort study.

Our findings suggest that higher folate and lower homocysteine levels, which reflected the interlinked folate and methionine cycles, was associated with higher fecundability in preconception women with lower IR, but less so in those with higher IR. Clinical Trial Registry number and website where it was obtained NCT03531658, /study/NCT03531658.

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The Association of Early Pregnancy Vitamin D and BMI Status with Composite Adverse Pregnancy Outcomes: an Ancillary Analysis of the Vitamin D Antenatal Asthma Reduction Trial.

While vitamin D supplementation did not reduce APO risk, higher early pregnancy 25(OH)D concentrations were associated with lower odds of APOs in participants with BMI <25 kg/m 2 . These findings highlight the potential importance of higher early pregnancy 25(OH)D concentrations, particularly among those with normal BMI, in reducing APO risk.

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The harms of high protein intake: conjectured, postulated, claimed, and presumed, but shown?

In this perspectives article, we discuss several of the postulated harms cited in academic and lay publications and investigate the strength of evidence to support or refute these asserted harms. We highlight areas of caution relating to experimental design and interpretation of results and propose areas of research that would be helpful to better determine the potential risks associated with high dietary protein intake.

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Inflamm Bowel Dis

18F-FAPI PET/CT for Early Detection and Severity Assessment of Intestinal Fibrosis in a Mouse Model.

As Crohn's disease (CD) with intestinal fibrosis progresses, 18F-FAPI uptake is high in the early stages and then gradually decreases. Activated fibroblasts appear more frequently in the early stages of intestinal fibrosis indicates that 18F-FAPI PET has a great potential for early identification of intestinal fibrosis and provides new insights into treatment decision-making in CD patients.

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Crohn's Disease Stricture Response to Treatment Assessed with Magnetic Resonance Imaging and Intestinal Ultrasound: STRIDENT Randomized Trial.

Radiologic severity of Crohn's disease strictures can improve with drug treatment, with complete stricture resolution observed in some. Intestinal ultrasound and MRI are effective modalities for monitoring the treatment response in patients with stricturing Crohn's disease (STRIDENT Drug Therapy Study NCT03220841).

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Disparities in Access and Treatment for Rural Patients With Inflammatory Bowel Disease: A Survey of Inflammatory Bowel Disease Patients and Providers.

These results demonstrate disparities between rural and urban patients' treatments and access to specialty IBD care. Rural patients and providers are supportive of collaborating with IBD specialists and MDTs. These results can help guide the implementation of innovative IBD care models in the setting of an increasingly complex IBD landscape.

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Innate and Adaptive Immunity is not Impacted by Inflammatory Bowel Disease Medications in Pregnant Women and Their Offspring.

This study provides the foundation for ongoing investigation to more definitively extricate the impact of maternal IBD activity, drug exposures, and disease phenotype on infant immune system development and function. These novel data suggest that IBD pharmacotherapies may not significantly impact maternal or infant immune regulation.

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Monitoring Structural Bowel Damage in Patients With Crohn's Disease Using Intestinal Ultrasonography: Can It Be Reversed by Biological Treatment?

Biological treatment can reverse SBD in CD, but hospitalizations and surgery rates remain higher in this group.

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Liver Transpl

Clinical and pathological spectrum of disease severity among patients with acute liver failure (ALF) undergoing deceased donor liver transplantation.

Virtually every patient undergoing liver transplantation for ALF retrospectively appeared to need their transplant, based on expert clinical consensus review. Overall, there was poor correlation between clinical severity and apparent degree of necrosis seen in the 300 liver explants, except perhaps for APAP subjects.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Inflamm Bowel Dis

AI-Assisted IBD Severity Classification: A Critical Perspective on Current Evidence and Next Steps.

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Maternal Microchimerism, a Red Flag or a Red Herring in Very-Early-Onset Inflammatory Bowel Disease?

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Past But Not Forgotten: Innate Factors Affect the Course of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Patients With Inflammatory Bowel Disease.

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J Crohns Colitis

Be precise, be reproducible! The emerging role of artificial intelligence in inflammatory bowel disease endoscopy.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…


Letters&Replies

Letters to the editors and authors’ replies